Avoiding bias in trials in which allocation ratio is varied.

© Doug Altman† Cite as: Altman DG† (2017). Avoiding bias in trials in which allocation ratio is varied. JLL Bulletin: Commentaries on the history of treatment evaluation (https://www.jameslindlibrary.org/articles/avoiding-bias-trials-allocation-ratio-varied/) Most randomised trials allocate participants equally to the interventions being compared – so the allocation ratio is 1:1 in a trial comparing two Read more…

Sample size calculation

One of the most critical aspects of planning a clinical study is the calculation of the sample size. As it is not possible to study the whole population in the study, a set of participants is selected (“sample”) from the population, which, although less in size, adequately represents the population Read more…

How to set up an RCT

So you want to set up a Randomized Controlled Trial. These are the steps you can follow: Gathering the Research Team. Determining the Research Question. Defining Inclusion and Exclusion Criteria. Randomization. Determining and Delivering the Intervention. Selecting the Control. Determining and Measuring Outcomes. Blinding Participants and Investigators. The RCT Builder Read more…

Run RCT Builder

After you have installed the RCT Builder you have to run the admin program /cmsb/admin.php with your Web Browser for the first time. The URL will probably look something like this: http://www.yourwebsitename.com/cmsb/admin.php The program will take you through the final steps of the installation. If you encounter any problems when Read more…

How to install RCT Builder

It is easy to install RCT builder in your server. To install the program, you will need:  The program zip and your Product ID PHP 7.1 or later PHP Extensions: mysqli, gd, curl, openssl, mbstring MySQL 5.5 or later Your MySQL server information: MySQL hostname (usually “localhost”) MySQL database name Read more…

Plugins

Plugins can increase RCT Builder functionality and broaden its potential. All of our add-on plugins have been created to extend the functionality of our solid, standalone CMS. We offer a wide selection of additional components that make it really simple to customize RCT Builder on a site-by-site basis. Licenses are Read more…

Server requirements

The software has been developed to work with virtually every single web server environment (Linux, Windows, and more). We’re confident you can run the software on your website, but if you want to make sure, here are the system requirements: Website – The software has to be installed on the actual Read more…